WebAntibodies raised against defined phosphorylation sites of the microtubule-associated protein tau are widely used in scientific research and being applied in clinical assays. However, recent studies have revealed an alarming degree of non-specific binding found in these antibodies. Websupplied by Innogenetics Formulation: liquid, PBS, sterile filtered, no preservative, affinity purified Reactivity: Reacts in: Human Immunogen/Epitope immunogen = human tau40, aa. around phospho.Thr 231 Specificity PHF tau and tau in tangles, phospho at Thr 231 Comments / Questions No Available Comments register. References Paper Citations
Validation of Tau Antibodies for Use in Western Blotting …
WebThis sequence is conserved in human (Ser633) and rat (Ser632) eNOS. WB (1:500). Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. WebAlexa Fluor® 647 Anti-Tau (phospho T205) antibody [EPR23505-13] (ab307376) Description: Alexa Fluor® 647 Rabbit monoclonal [EPR23505-13] to Tau (phospho T205) Application: IHC-Fr, IHC-P. Reactivity: Mouse, Rat, Human. Conjugate: Alexa Fluor® 647. Recombinant 10 µl … inceptra webinars
Phospho-Tau (Thr231) Antibody Cell Signaling Technology
WebPhospho-Tau (Ser404) (D2Z4G) Rabbit mAb recognizes endogenous levels of tau protein when phosphorylated at Ser404. This antibody detects single phosphorylation at Ser404, dual phosphorylation at Ser400/Ser404 or Thr403/Ser404, and triple phosphorylation at Ser400/Thr403/Ser404. WebAll synaptic proteins contain a short amino-terminal domain, which is highly conserved and phosphorylated by PKA or CaM kinase i. The phosphorylation of the amino terminal serine 9 of synapse protein can inhibit its binding to phospholipids and separate synapse protein from synaptic vesicles. Immunogen. Phosphopeptide surrounding serine 9 of ... WebFeb 15, 2024 · A majority of antibodies use a single CDR loop for phosphate recognition, but for the antibody dmCBTAB-22.1 (targeting phospho-serine (pSer) 422 tau), residues in CDR H1 and H3 both form hydrogen bonds with the phosphate ( Fig. 1f) [ 35 ]. inceptor torrent