Dachshund family transcription factor
WebIn breast cancer cells, DACH1 opposed SIX1 action, via transcriptional repression of common targets, including CCND1 and IL8 (interleukin 8) to inhibit cell proliferation and migration in vitro, as well as tumor growth and metastases in vivo ( Popov et al., 2010; Wu et al., 2008, 2006, 2007, 2003 ). WebDACH2: dachshund family transcription factor 2 Summary. This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain ...
Dachshund family transcription factor
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WebDachshunds are bred with the chondrodysplasia (dwarfism) gene, so it takes longer than normal for their legs to fully develop. Once they’re born, dachshund puppies start growing rapidly for the first 8 months or so. … WebDACH2, dachshund family transcription factor 2 Vertebrate Orthologs 3 Mutations, Alleles, and Phenotypes less Phenotype Summary 1 phenotype from 2 alleles in 2 genetic backgrounds 5 phenotype references All Mutations and Alleles 4 Endonuclease-mediated 2 Targeted 2 Incidental Mutations CvDC Find Mice (IMSR)
WebDescription. enhancer of zeste 2 polycomb repressive complex 2 subunit This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ... WebNotably, a result of the present study was that the cell fate determination factor dachshund family transcription factor 1 (DACH1) was identified as a direct target of miR-200c. Suppression of miR-200c expression in NPC cells increased endogenous DACH1 mRNA and protein levels, which was negatively correlated with miR-200c.
Webdachshund (dac) is a gene involved in the development of the arthropod compound eye which also plays a role in leg development. It is activated by the Distal-less (Dll) gene. … WebMay 17, 2024 · Here, we performed transcriptome-wide association studies (TWAS), summary Mendelian randomization, and MetaXcan to identify genes whose expression mediates the genotype effect on the phenotype. Our analyses identified Dachshund homolog 1 (DACH1), a cell-fate determination factor.
WebDec 13, 2024 · Immunoglobulin A nephropathy (IgAN) is a kidney disease and one of the commonest forms of glomerulonephritis worldwide. The present study investigated the role of dachshund family transcription...
Gene structure . This protein coding gene has 760 amino acid protein, and an observed molecular weight of 52 kDa. Dachshund Family transcription factor 1 is encoded by DACH gene, who spans 400kDa and is encoded by 12 exons. This gene is located, in humans, in chromosome 13 (13q22). It encodes a chromatin-associated protein that associates with other DNA-binding transcription factors t… i really love you norman hutchins lyricsWebJul 1, 2008 · DACH1 (dachshund family transcription factor 1) 2008-07-01 Affiliation Identity. HGNC. DACH1. LOCATION. 13q21.33. LOCUSID. 1602. ALIAS. DACH. FUSION … i really love you you should knowhttp://www.informatics.jax.org/marker/MGI:1890446 i really love your bodyWebJustin P. Kumar, in Current Topics in Developmental Biology, 2010 4.3 Dac: A transcription factor in search of a target. While a requirement for dac in eye specification and … i really miss my niggaaaa fullWebJul 1, 2008 · DACH1 (dachshund family transcription factor 1) 2008-07-01 Affiliation Identity HGNC DACH1 LOCATION 13q21.33 LOCUSID 1602 ALIAS DACH FUSION GENES Show Gene Fusions Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool Other … i really miss my mistressWebDACH1, dachshund family transcription factor 1 Vertebrate Orthologs 4 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog DACH1, dachshund … i really miss my dawgsWebWe have isolated mammalian homologues of the Drosophila dachshund gene. Two domains of high conservation, one of which contains an alpha-helical, coiled-coil motif, show … i really miss being a kid